TB Education and Training Resource Guide—MULTIDRUG-RESISTANT TB (Printable Version)
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Drug Resistance: Aminosalicyclic Acid (PAS) Granules for Treatment
This fact sheet discusses the use of the second-line drug aminosalicyclic acid
(PAS) granules for the treatment of persons with multidrug-resistant TB. It
reviews the history of PAS as an anti-TB drug and explains the dosing regimen
(New York City Department of Health, 2001).
Audience: health professionals, physicians
Format: fact sheet, 1 p
Language: English
Internet link: www.nyc.gov/html/doh/html/tb/tb4b.html
Available from: New York City Department of Health and Mental Hygiene,
Tuberculosis Control Program, 125 Worth St, New York, NY 10013; 212-442-9968;
www.nyc.gov/html/doh/html/tb/tb.html
Drug Resistance: Fluoroquinolone Resistance and TB Treatment
This fact sheet discusses precautions against the development of flouroquinolone-resistant
TB (New York City Department of Health, 2000).
Audience: health professionals, physicians
Format: fact sheet, 2 pp
Language: English
Internet link: www.nyc.gov/html/doh/html/tb/tbfs.html
Available from: New York City Department of Health and Mental Hygiene,
Tuberculosis Control Program, 125 Worth St, New York, NY 10013; 212-442-9968;
www.nyc.gov/html/doh/html/tb/tb.html
Drug Resistance: Multidrug-Resistant Tuberculosis
This fact sheet explains multidrug-resistant TB, examines its emergence, and
describes elements of infection control that have helped to stem its spread
(New York City Department of Health, 2001).
Audience: health professionals, physicians
Format: fact sheet, 2 pp
Language: English
Internet link: www.nyc.gov/html/doh/html/tb/tb4c.html
Available from: New York City Department of Health and Mental Hygiene,
Tuberculosis Control Program, 125 Worth St, New York, NY 10013; 212-442-9968;
www.nyc.gov/html/doh/html/tb/tb.html
Epidemiologic Notes and Reports: Nosocomial Transmission of Multidrug-Resistant
Tuberculosis among HIV-Infected Persons-Florida and New York, 1988-1991. Morbidity
and Mortality Weekly Report. 40(34):585-591, August 30, 1991

This report discusses outbreaks of multidrug-resistant TB in four hospitals
and presents recommendations for prevention and control of such outbreaks (Centers
for Disease Control and Prevention, 1991).
Audience: health professionals, nurses, physicians
Format: report, 5 pp
Language: English
Internet link: www.cdc.gov/nchstp/tb/pubs/mmwrhtml/mmwr_mdrtb.htm
Available from: Massachusetts Medical Society, 860 Winter St, Waltham
Woods Corporate Center, Waltham, MA 02451-1411; 800-843-6356; www.massmed.org.
Paper copies of single issues cost $5.25.
and U.S. Government Printing Office (GPO), Washington, D.C.
20402; 866-512-1800; www.gpo.gov. GPO provides
a CD-ROM containing MMWRs from 1991 to 1997 for $19. Request item #017-022-01418-1.
Epidemiologic Notes and Reports: Transmission of Multidrug-Resistant
Tuberculosis from an HIV-Positive Client in a Residential Substance-Abuse Treatment
Facility-Michigan. Morbidity and Mortality Weekly Report. 40(08):129-131,
March 1, 1991 
This report describes a case in which multidrug-resistant TB was transmitted
from an HIV-positive injection drug user to clients and staff at a residential
substance abuse treatment facility (Centers for Disease Control and Prevention,
1991).
Audience: health professionals, nurses, physicians
Format: report, 3 pp
Language: English
Internet link: www.cdc.gov/nchstp/tb/pubs/mmwrhtml/mmwr_mdrtb.htm
Available from: Massachusetts Medical Society, 860 Winter St, Waltham
Woods Corporate Center, Waltham, MA 02451-1411; 800-843-6356; www.massmed.org.
Paper copies of single issues cost $5.25.
and U.S. Government Printing Office (GPO), Washington, D.C.
20402; 866-512-1800; www.gpo.gov. GPO provides
a CD-ROM containing MMWRs from 1991 to 1997 for $19. Request item #017-022-01418-1.
Management of Persons Exposed to Multidrug-Resistant Tuberculosis.
Morbidity and Mortality Weekly Report. 41(RR-11), June 19, 1992

This CDC guideline offers suggestions for evaluating and managing persons who
have been exposed to patients with infectious multidrug-resistant TB (Centers
for Disease Control and Prevention, 1992).
Audience: health professionals, nurses, physicians
Format: guideline, 10 pp
Language: English
Internet link: www.cdc.gov/nchstp/tb/pubs/mmwrhtml/maj_guide.htm
Available from: CDC National Center for HIV, STD, and TB Prevention (NCHSTP).
Materials can be ordered in a number of ways: 1) By accessing the online order
form at www.cdc.gov/nchstp/tb. 2)
by calling the CDC voice and fax information system (recording) toll-free at
888-232-3228, then pressing options 2, 5, 1, 2, 2; 3) by faxing a request for
material to the NCHSTP Office of Communications at 404-639-8910; or 4) by mailing
a request to the CDC NCHSTP Office of Communications at 1600 Clifton Rd, NE,
MS E-07, Atlanta, GA 30333. Request item #00-6225.
and CDC National Prevention Information Network, PO Box 6003,
Rockville, MD 20849-6003; 800-458-5231; www.cdcnpin.org.
Request inventory item #M032.
and Massachusetts Medical Society, 860 Winter St, Waltham
Woods Corporate Center, Waltham, MA 02451-1411; 800-843-6356; www.massmed.org.
Paper copies of single issues cost $5.25.
and U.S. Government Printing Office (GPO), Washington, D.C.
20402; 866-512-1800; www.gpo.gov. GPO provides
a CD-ROM containing MMWRs from 1991 to 1997 for $19. Request item #017-022-01418-1.
Multi-Drug-Resistant Tuberculosis 
This report reviews the causes, treatment, and control of multidrug-resistant
TB and describes recent outbreaks (Centers for Disease Control and Prevention,
1994).
Audience: physicians
Format: report, 9 pp
Language: English
Available from: CDC National Center for HIV, STD, and TB Prevention (NCHSTP).
Materials can be ordered in a number of ways: 1) By accessing the online order
form at www.cdc.gov/nchstp/tb; 2)
by calling the CDC voice and fax information system (recording) toll-free at
888-232-3228, then pressing options 2, 5, 1, 2, 2; 3) by faxing a request for
material to the NCHSTP Office of Communications at 404-639-8910; or 4) by mailing
a request to the CDC NCHSTP Office of Communications at 1600 Clifton Rd, NE,
MS E-07, Atlanta, GA 30333. Request item #00-6529.
and CDC National Prevention Information Network, PO Box 6003,
Rockville, MD 20849-6003; 800-458-5231; www.cdcnpin.org.
Request inventory item #D341.
Multidrug-Resistant Tuberculosis in a Hospital—Jersey City, New
Jersey, 1990 1992. Morbidity and Mortality Weekly Report. 43(22):417
419, June 10, 1995 
This report presents the findings of a study of patients treated at the Jersey
City Medical Center and compares the hospital’s rates of drug-resistant
TB with previously reported rates, rates for other cities in New Jersey, and
rates for the state (Centers for Disease Control and Prevention, 1994).
Audience: health professionals, nurses, physicians
Format: report, 3 pp
Language: English
Internet link: www.cdc.gov/nchstp/tb/pubs/mmwrhtml/mmwr_mdrtb.htm
Available from: Massachusetts Medical Society, 860 Winter St, Waltham
Woods Corporate Center, Waltham, MA 02451-1411; 800-843-6356; www.massmed.org.
Paper copies of single issues cost $5.25.
and U.S. Government Printing Office (GPO), Washington, D.C.
20402; 866-512-1800; www.gpo.gov. GPO provides
a CD-ROM containing MMWRs from 1991 to 1997 for $19. Request item #017-022-01418-1.
National Action Plan to Combat Multidrug-Resistant Tuberculosis. Morbidity
and Mortality Weekly Report. 41(RR-11):5-48, June 19, 1992

This CDC report identifies objectives and recommends national activities for
the control of multidrug-resistant TB (Centers for Disease Control and Prevention,
1992).
Audience: advocates, government agencies, health professionals, policy
makers
Format: report, 48 pp
Language: English
Internet link: www.cdc.gov/nchstp/tb/pubs/mmwrhtml/maj_guide.htm
Available from: CDC National Center for HIV, STD, and TB Prevention (NCHSTP).
Materials can be ordered in a number of ways: 1) By accessing the online order
form at www.cdc.gov/nchstp/tb. 2)
by calling the CDC voice and fax information system (recording) toll-free at
888-232-3228, then pressing options 2, 5, 1, 2, 2; 3) by faxing a request for
material to the NCHSTP Office of Communications at 404-639-8910; or 4) by mailing
a request to the CDC NCHSTP Office of Communications at 1600 Clifton Rd, NE,
MS E-07, Atlanta, GA 30333. Request item #00-6224.
and Massachusetts Medical Society, 860 Winter St, Waltham
Woods Corporate Center, Waltham, MA 02451-1411; 800-843-6356; www.massmed.org.
Paper copies of single issues cost $5.25.
and U.S. Government Printing Office (GPO), Washington, D.C.
20402; 866-512-1800; www.gpo.gov. GPO provides
a CD-ROM containing MMWRs from 1991 to 1997 for $19. Request item #017-022-01418-1.
Outbreak of Multidrug-Resistant Tuberculosis at a Hospital-New York
City, 1991. Morbidity and Mortality Weekly Report. 42(22):427-434, June
11, 1993 
This report summarizes an epidemiologic investigation at a New York City hospital
and presents information on 32 patients at that hospital who were diagnosed
with multidrug-resistant TB (Centers for Disease Control and Prevention, 1993).
Audience: health professionals, nurses, physicians
Format: report, 8 pp
Language: English
Internet link: www.cdc.gov/nchstp/tb/pubs/mmwrhtml/mmwr_mdrtb.htm.
Available from: Massachusetts Medical Society, 860 Winter St, Waltham
Woods Corporate Center, Waltham, MA 02451-1411; 800-843-6356; www.massmed.org.
Paper copies of single issues cost $5.25.
and U.S. Government Printing Office (GPO), Washington, D.C.
20402; 866-512-1800; www.gpo.gov. GPO provides
a CD-ROM containing MMWRs from 1991 to 1997 for $19. Request item #017-022-01418-1.
Probable Transmission of Multidrug-Resistant Tuberculosis in a Correctional
Facility-California. Morbidity and Mortality Weekly Report. 42(03):48-51,
January 29, 1993 
This report presents findings of a state and local health department investigation
into the possibility of nosocomical TB transmission from inmates to staff in
a California correctional facility from 1990 to 1991 (Centers for Disease Control
and Prevention, 1993).
Audience: health professionals
Format: report, 4 pp
Language: English
Internet link: www.cdc.gov/mmwr/PDF/wk/mm4203.pdf
Available from: Massachusetts Medical Society, 860 Winter St, Waltham
Woods Corporate Center, Waltham, MA 02451-1411; 800-843-6356; www.massmed.org.
Paper copies of single issues cost $5.25.
and U.S. Government Printing Office (GPO), Washington, D.C.
20402; 866-512-1800; www.gpo.gov. GPO provides
a CD-ROM containing MMWRs from 1991 to 1997 for $19. Request item #017-022-01418-1.
Timebomb: The Global Epidemic of Multi-Drug-Resistant Tuberculosis
This book discusses the developing epidemic of multidrug-resistant TB and examines
how the HIV/AIDS epidemic has affected the resurgence of TB (McGraw Hill, 2002).
Audience: general public, government agencies, health professionals,
physicians
Format: book, 272 pp
Language: English
Available from: McGraw-Hill Companies, PO Box 182604, Columbus, OH 43272;
877-833-5524; www.mcgraw-hill.com
Transmission of Multidrug-Resistant Tuberculosis among Immunocompromised
Persons in a Correctional System-New York, 1991. Morbidity and Mortality
Weekly Report. 41(28):507-509, July 17, 1992 
This report summarizes preliminary results of an investigation of multidrug-resistant
TB in a correctional facility in New York (Centers for Disease Control and Prevention,
1992).
Audience: health professionals, nurses, physicians
Format: report, 3 pp
Language: English
Internet link: www.cdc.gov/nchstp/tb/pubs/mmwrhtml/mmwr_mdrtb.htm.
Available from: Massachusetts Medical Society, 860 Winter St, Waltham
Woods Corporate Center, Waltham, MA 02451-1411; 800-843-6356; www.massmed.org.
Paper copies of single issues cost $5.25.
and U.S. Government Printing Office (GPO), Washington, D.C.
20402; 866-512-1800; www.gpo.gov. GPO provides
a CD-ROM containing MMWRs from 1991 to 1997 for $19. Request item #017-022-01418-1.
Treatment of Drug-Resistant Tuberculosis

This fact sheet, available online or via fax only, discusses treatment of latent
TB infection and drug-resistant TB. It also discusses treating drug-resistant
TB in those with HIV co-infection (Centers for Disease Control and Prevention,
2000).
Audience: health professionals, nurses, occupational health and infection
control workers, physicians
Format: fact sheet, 3 pp
Language: English
Internet link: www.cdc.gov/nchstp/tb/pubs/dtbefax.htm.
Available from: Centers for Disease Control and Prevention. To receive
this document by fax, call 888-CDC-FAXX (888-232-3299). At the prompt, request
item #250112.