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TB Education and Training Resource Guide—DIAGNOSIS (Printable Version)

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General TB Diagnosis

Diagnosis General TB Diagnosis Diagnosis: Reporting Requirements for Tuberculosis
This fact sheet provides information on TB reporting requirements in New York City. It explains the importance of epidemiological reporting and identifies factors that mandate a case to be reported (New York City Department of Health, 2001).
Audience: health professionals, nurses, physicians
Format: fact sheet, 2 pp
Language:        English
Internet link: www.nyc.gov/html/doh/html/tb/tb1f.html
Available from:    New York City Department of Health and Mental Hygiene, Tuberculosis Control Program, 125 Worth St, New York, NY 10013; 212-442-9968; www.nyc.gov/html/doh/html/tb/tb.html

Diagnosis of Latent TB Infection and TB Disease CDC Icon
This fact sheet, available online or via fax only, discusses the tuberculin skin test and when to suspect TB disease. Specifically, it discusses administering the tuberculin skin test, interpreting the results, false-positive and false-negative results, two-step testing, anergy, and interpreting reactions in persons vaccinated with BCG (Centers for Disease Control and Prevention, 2000).
Audience: health professionals, nurses, occupational health and infection control workers, physicians
Format: fact sheet, 4 pp
Language:        English
Internet link: www.cdc.gov/nchstp/tb/pubs/dtbefax.htm
Available from:    Centers for Disease Control and Prevention.
To receive this document by fax, call 888-CDC-FAXX (888 -232-3299). At the prompt, request item #250102.

Diagnosis and Treatment of Latent Tuberculosis Infection in the 21st Century: An Audio Recording for Clinicians
This course discusses the diagnosis and treatment of latent TB infection. It presents major risk factors for developing active TB disease after latent TB infection has been contracted (Francis J. Curry National Tuberculosis Center, 2000).
Audience: health professionals, nurses, physicians
Format: audiotape, course
Language:        English
Available from:    Francis J. Curry National Tuberculosis Center, 3180 18th St, Ste 101, San Francisco, CA 94110-2028; 415-502-4600; www.nationaltbcenter.edu

Diagnostic Standards and Classification of Tuberculosis in Adults and Children. American Journal of Respiratory and Critical Care Medicine. 161:1376-1395, 2000 CDC Icon
This guideline is intended to provide a framework and understanding of the diagnostic approaches to TB infection/disease and to present a classification scheme that facilitates management of all persons who have had diagnostic tests (American Thoracic Society and the Centers for Disease Control and Prevention, 2000).
Audience: health professionals, nurses, physicians
Format: guideline, 20 pp
Language:        English
Internet link: www.cdc.gov/nchstp/tb/pubs/1376.pdf
Available from:    CDC National Prevention Information Network, PO Box 6003, Rockville, MD 20849-6003; 800-458-5231; www.cdcnpin.org. Request inventory item #D380.

Testing for Tuberculosis CDC Icon
This fact sheet, available online or via fax only, discusses TB testing for health care workers, people at high risk, and people with latent TB infection or active TB disease (Centers for Disease Control and Prevention, 2000).
Audience: health professionals, occupational health and infection control workers
Format: fact sheet, 3 pp
Language:        English
Internet link: www.cdc.gov/nchstp/tb/pubs/dtbefax.htm
Available from:    Centers for Disease Control and Prevention.
To receive this document by fax, call 888-CDC-FAXX (888 -232-3299). At the prompt, request item #250140.

 

Tuberculin Skin Testing

Materials providing information on the BCG vaccine are covered in the “Bacille Calmette-Guerin (BCG) and Other Vaccines” section, beginning page 169. Materials providing information on TB screening appear in the “Screening” section, beginning page 88.

Anergy Skin Testing and Preventive Therapy for HIV-Infected Persons: Revised Recommendations. Morbidity and Mortality Weekly Report. 46(RR-15):1-10, September 5, 1997 CDC Icon
This CDC guideline replaces previous recommendations for the use of anergy skin testing together with purified protein derivative-tuberculin skin testing of HIV-positive persons (Centers for Disease Control and Prevention, 1997).
Audience: health professionals, nurses, physicians
Format: guideline, 19 pp
Language:        English
Internet link: www.cdc.gov/nchstp/tb/pubs/mmwrhtml/maj_guide.htm
Available from:    CDC National Center for HIV, STD, and TB Prevention (NCHSTP). Materials can be ordered in a number of ways: 1) By accessing the online order form at www.cdc.gov/nchstp/tb; 2) by calling the CDC voice and fax information system (recording) toll-free at 888-232-3228, then pressing options 2, 5, 1, 2, 2; 3) by faxing a request for material to the NCHSTP Office of Communications at 404-639-8910; or 4) by mailing a request to the CDC NCHSTP Office of Communications at 1600 Clifton Rd, NE, MS E-07, Atlanta, GA 30333. Request item #9954-12.    
and   Massachusetts Medical Society, 860 Winter St, Waltham Woods Corporate Center, Waltham, MA 02451-1411; 800-843-6356; www.massmed.org. Paper copies of single issues cost $5.25.    
and   U.S. Government Printing Office (GPO), Washington, D.C. 20402; 866-512-1800; www.gpo.gov. GPO provides a CD-ROM containing MMWRs from 1991 to 1997 for $19. Request item #017-022 -01418-1.

Diagnosis: Tuberculin Skin Testing for Suspected TB
This fact sheet discusses the use of the TB skin test, explains the importance of delivering the test to individuals suspected of having TB, and identifies the test’s diagnostic disadvantages (New York City Department of Health, 2001).
Audience: health professionals, nurses, physicians
Format: fact sheet, 1 p
Language:        English
Internet link: www.nyc.gov/html/doh/html/tb/tb1c.html
Available from:    New York City Department of Health and Mental Hygiene, Tuberculosis Control Program, 125 Worth St, New York, NY 10013; 212-442-9968; www.nyc.gov/html/doh/html/tb/tb.html

Infection Control: Tuberculosis Surveillance of Health Care Workers—Tuberculin Skin Testing
This fact sheet discusses the TB skin test, explains the need to screen health care workers regularly for TB, and lists those individuals most likely to be exposed to TB (New York City Department of Health, 2001).
Audience: health professionals, nurses, physicians
Format: fact sheet, 2 pp
Language:        English
Internet link: www.nyc.gov/html/doh/html/tb/tb5b.html
Available from:    New York City Department of Health and Mental Hygiene, Tuberculosis Control Program, 125 Worth St, New York, NY 10013; 212-442-9968; www.nyc.gov/html/doh/html/tb/tb.html

Mantoux Tuberculin Skin Test CDC Icon
This videotape provides a clear, detailed demonstration of the steps involved in administering and reading the Mantoux tuberculin skin test (Centers for Disease Control and Prevention, 2002).
Audience: health professionals, nurses, physicians
Format: videotape, 30 min
Language:        English
Available from:    CDC National Center for HIV, STD, and TB Prevention (NCHSTP). Materials can be ordered in a number of ways: 1) By accessing the online order form at www.cdc.gov/nchstp/tb; 2) by calling the CDC voice and fax information system (recording) toll-free at 888-232-3228, then pressing options 2, 5, 1, 2, 2; 3) by faxing a request for material to the NCHSTP Office of Communications at 404-639-8910; or 4) by mailing a request to the CDC NCHSTP Office of Communications at 1600 Clifton Rd, NE, MS E-07, Atlanta, GA 30333. Request item #00-5457.    
and   CDC National Prevention Information Network, PO Box 6003, Rockville, MD 20849-6003; 800-458-5231; www.cdcnpin.org. Request inventory item #V468.

Mantoux Tuberculin Skin Test CDC Icon
This poster illustrates and describes proper tuberculin testing and reading procedures (Centers for Disease Control and Prevention, 1991).
Audience: health professionals, physicians
Format: poster, 17" X 14"
Language:        English
Internet link: www.cdc.gov/nchstp/tb
Available from:    CDC National Center for HIV, STD, and TB Prevention (NCHSTP). Materials can be ordered in a number of ways: 1) By accessing the online order form at www.cdc.gov/nchstp/tb; 2) by calling the CDC voice and fax information system (recording) toll-free at 888-232-3228, then pressing options 2, 5, 1, 2, 2; 3) by faxing a request for material to the NCHSTP Office of Communications at 404-639-8910; or 4) by mailing a request to the CDC NCHSTP Office of Communications at 1600 Clifton Rd, NE, MS E-07, Atlanta, GA 30333. Request item #00-5564.

Mantoux Tuberculin Skin Test Class (for MDs, RNs, and LPNs)
This instructional packet was designed to educate health professionals about properly administering and interpreting the Mantoux skin test for TB (County of San Diego Health and Human Services Agency, 1996).
Audience: health professionals, nurses, physicians
Format: instructional packet, 12 pp
Language:        English
Available from:    County of San Diego Health and Human Services Agency, Office of Public Health,
Tuberculosis Control Program, PO Box 85222, San Diego, CA 92816; 619-692-5565;
www.co.san-diego.ca.us/cnty/cntydepts/health/services/tb/index.htm

TB Test Card
This card provides a place for health professionals to record tuberculin skin test results and, if the patient tests positive, the medical treatment being administered (North Carolina Department of Health and Human Services, 1997).
Audience: health professionals, Hispanics, nurses, physicians
Format: information card
Language:      English, Spanish
Available from:    North Carolina Department of Health and Human Services, Communicable Disease Control Branch, TB Control Program, 1902 Mail Service Center, Raleigh, NC 27699-1902; 919-733-7286; www.dhhs.state.nc.us

Tuberculin Skin Testing (TST): Standard Therapy for TB Disease
This information card provides directions for administering and reading the tuberculin skin test (North Carolina Department of Health and Human Services, 1998).
Audience: health professionals, nurses, physicians
Format: information card, 4 pp
Language:        English
Available from:    North Carolina Department of Health and Human Services, Communicable Disease Control Branch, TB Control Program, 1902 Mail Service Center, Raleigh, NC 27699-1902; 919-733-7286; www.dhhs.state.nc.us

Tuberculosis Skin Testing (TST): Tools for Training
This collection of training tools, available online only, is designed to help experienced TB nurses and program staff. It includes a section designed for trainers and a section with materials for health care professionals (trainees) (Francis J. Curry National Tuberculosis Center, 2002).
Audience: health educators/communicators, health professionals, nurses
Format: teaching guide
Language:        English
Internet link: www.nationaltbcenter.edu/catalogue/epub/tst/index.html

Tuberculosis Update and Tuberculin Skin Testing Certification
This teaching guide and pamphlet provide basic information about TB and information regarding TB skin testing certification (Mississippi State Department of Health, 2001).
Audience: health professionals, nurses, physicians
Format: pamphlet, 6 pp; teaching guide, 14 pp
Language:        English
Available from:    Mississippi State Department of Health, Tuberculosis Control Branch, PO Box 1700, Jackson, MS 39215-1700; 601-576-7400; www.msdh.state.ms.us

Two-Step Testing: Nursing Home and Rest Home Residents
This fact sheet discusses the rationale and procedures for two-step TB skin testing for nursing and rest home residents (Massachusetts Department of Public Health, 2001).
Audience: health professionals
Format: fact sheet, 1 p
Language:        English
Available from:    Massachusetts Department of Public Health, Division of Tuberculosis Control, 305 South St, Jamaica Plain, MA 02130; 617-983-6970; www.state.ma.us/dph/dphhome.htm

TB Skin Testing Tools

Practice Arms

BIOLIKE TB Testing Arm Set
These arms, made of the material BIOLIKE™, simulate the touch and feel of skin. Each arm has four different size indurations and comes with an instruction card.
Audience: health professionals, nurses, physicians
Format:       tool
Language:        English
Available from:    Health Edco, Division of WRS Group, Ltd., PO Box 21207, Waco, TX 76702-1207; 800-299-3366 ext 295; www.healthedco.com

Life/Form Advanced Injection Arm
The arm is designed for practicing IV therapy, phlebotomy, and intramuscular and intradermal injections. Available in white or black, it includes two quarts of simulated blood, a 3 cc syringe, a 12 cc syringe, two fluid bags, and a carrying case. Intradermal injections of a specially supplied fluid will create characteristic skin welts at designated sites on the upper arm.
Audience: health professionals, nurses, physicians
Format:       tool
Available from:    Nasco Health Care Educational Materials, 901 Janesville Ave, Fort Atkinson, WI 53538-0901; 800-558-9595 or 920-563-2446; www.enasco.com/prod/Home. For West coast orders: 4825 Stoddard Rd, PO Box 3837, Modesto, CA 95352-3837; 800-558-9595 or 209-545-1600.

See and Touch Arms
These are replicas of full-size arms from fist to above the elbow. The arms come with one of four skin tones, a base to hold the arm, and a carrying case. Sets of two arms are also available with bases and carrying case.
Audience: health professionals, nurses, physicians
Format:       tool
Available from:    American Respiratory Alliance of Western Pennsylvania, Cranberry Professional Park, 201 Smith Dr, Ste E, Cranberry Township, PA 16066; 800-220-1990 or 724-772-1750; www.healthylungs.org

TB Testing Arm Set
This aid is a replica of the upper part of the forearm only. It is made to lie flat on a table and to fit easily into a brief case or tote bag. Each arm has four different indurations. A set of one beige and one brown arm is available.
Audience:       health professionals, nurses, physicians
Format:       tool
Available from:    Health Edco, Division of WRS Group, Ltd., PO Box 21207, Waco, TX 76702-1207; 800-299-3366 ext 295; www.healthedco.com

Skin Testing Rulers

Aplisol for Mantoux Testing
This caliper ruler slides so that pincers can be placed around the induration of an individual’s reaction to the tuberculin skin test. The measurement in millimeters corresponds to the width of the pincers around the induration.
Audience:         health professionals, nurses, physicians
Format:       tool
Available from:     Monarch Pharmaceuticals, 100 18th St, Bristol, TN 37620; 800-776-3637; www.kingpharm.com/default_king.htm

Division of TB Prevention and Control
This caliper ruler is a round disc that swivels to form pincers that can be placed around the induration of an individual’s reaction to the tuberculin skin test. The measurement in millimeters corresponds to the width of the pincers around the induration. One side is solid and the other is clear plastic. The measuring device includes contact information for TB control in Massachusetts and tips for reading the skin test reaction.
Audience:         health professionals, nurses, physicians
Format:       tool
Available from:     Massachusetts Department of Public Health, Division of Tuberculosis Control, 305 South St, Jamaica Plain, MA 02130; 617-983-6970; www.state.ma.us/dph/dphhome.htm

Don’t Let TB Rule
This caliper ruler is 6.5" X 3.5" with two pieces that swivel to form large moving pincers. The pincers can be placed around the induration of an individual’s reaction to the tuberculin skin test. The measurement in millimeters corresponds to the width of the pincers around the induration. The measurement device includes tips for reading the skin test reaction, contact information for the Connecticut American Lung Association and TB program, and information on who is considered positive.
Audience:         health professionals, nurses, physicians
Format:       tool
Available from:     American Lung Association of Connecticut, 45 Ash St, East Hartford, CT 06108-2372; 800-LUNG-USA, 860-289-5407; www.alact.org

State of New York Department of Health Tuberculosis Control
This caliper ruler is a round disc that swivels to form pincers that can be placed around the induration of an individual’s reaction to the tuberculin skin test. The measurement in millimeters corresponds to the width of the pincers around the induration. The back of the disc includes information on interpretation and contact information for TB control in New York.
Audience:         health professionals, nurses, physicians
Format:       tool
Available from:     New York State Department of Health, Bureau of TB Control, Corning Tower, Rm 840, Empire State Plaza, Albany, NY 12237-0669; 518-474-4845; www.health.state.ny.us/home.html

Straight-Edge Ruler (What is Positive?)
This traditional-style ruler has gradations marked in millimeters along the straight edge. It is used to measure the induration of an individual’s reaction to the TB skin test.
Audience: health professionals, nurses, physicians
Format:       tool
Available from:    California Tuberculosis Controllers Association, 2151 Berkeley Way, Rm 608, Berkeley, CA 94704-1011; 510-540-2722; www.ctca.org

Tuberculin Skin Test Ruler CDC Icon
This straight-edge ruler is used to measure the induration of an individual’s reaction to the tuberculin skin test. The white ruler provides tips on how to read the test and a space for local contact information to be inscribed with a permanent marker (Centers for Disease Control and Prevention, 2002).
Audience: health professionals, nurses, physicians
Format:       tool
Language:        English
Available from:    CDC National Center for HIV, STD, and TB Prevention (NCHSTP). Materials can be ordered in a number of ways: 1) By accessing the online order form at www.cdc.gov/nchstp/tb; 2) by calling the CDC voice and fax information system (recording) toll-free at 888-232-3228, then pressing options 2, 5, 1, 2, 2; 3) by faxing a request for material to the NCHSTP Office of Communications at 404-639-8910; or 4) by mailing a request to the CDC NCHSTP Office of Communications at 1600 Clifton Rd, NE, MS E-07, Atlanta, GA 30333. Request item #99-7047.

Tubersol Ruler
This clear straight-edge ruler is used to measure the induration of an individual’s reaction to the tuberculin skin test. The ruler includes four tips on placing, injecting, reading, and recording.
Audience:         health professionals, nurses, physicians
Format:       tool
Available from:     Aventis Pasteur, Inc., Customer Service, Discovery Dr, Swiftwater, PA 18370; 800-822-2463, 570-839-5000

Screening

ACHA Guidelines: Tuberculosis Screening on Campus
This fact sheet provides guidelines for screening college students for TB in the United States (American College Health Association, 1996).
Audience: health educators/communicators
Format: fact sheet, 2 pp
Language:        English
Available from:    American College Health Association, Task Force on HIV Disease and AIDS, PO Box 28937, Baltimore, MD 21240-8937; 410-859-1500; www.acha.org

A Guideline for Establishing Effective Practices: Identifying Persons with Infectious TB in the Emergency Department
This guideline helps emergency department personnel establish effective TB control practices for early identification of patients with infectious TB. It describes how to assess and evaluate TB transmission risk in the emergency department, implement isolation and diagnostic procedures, and implement TB triage procedures (Francis J. Curry National Tuberculosis Center, 1999).
Audience: health educators/communicators, health professionals, nurses, occupational health and infection control workers, physicians
Format: guideline, 59 pp (includes case studies, worksheets, and sample posters)
Language:        English
Internet link: www.nationaltbcenter.edu/catalogue/workplace_tools.cfm
Available from:    Francis J. Curry National Tuberculosis Center, 3180 18th St, Ste 101, San Francisco, CA 94110-2028; 415-502-4600; www.nationaltbcenter.edu

Infection Control: Tuberculosis Surveillance of Health Care Workers—Tuberculin Skin Testing
This fact sheet explains the need to screen health care workers regularly for TB and lists those individuals most likely to be exposed to TB (New York City Department of Health, 2001).
Audience: health professionals, physicians
Format: fact sheet, 2 pp
Language:        English
Internet link: www.nyc.gov/html/doh/html/tb/tb5b.html
Available from:    New York City Department of Health and Mental Hygiene, Tuberculosis Control Program, 125 Worth St, New York, NY 10013; 212-442-9968; www.nyc.gov/html/doh/html/tb/tb.html

Policy and Procedures for Tuberculosis Screening of Health Care Workers
This guideline provides health care facility administrators with a template for policies and procedures related to screening health care workers for TB and designing, implementing, and documenting an effective TB screening program for this population (Francis J. Curry National Tuberculosis Center, 1999).
Audience: health professionals, managers and supervisors, occupational health and infection control workers
Format: guideline, 117 pp
Language:        English
Available from:     Francis J. Curry National Tuberculosis Center, 3180 18th St, Ste 101, San Francisco, CA 94110-2028; 415-502-4600; www.nationaltbcenter.edu

Screening for Tuberculosis in Infants and Children. Pediatrics. 93:131-134
This report examines issues related to screening children and infants for TB (American Academy of Pediatrics, 1994).
Audience: health professionals, physicians
Format: report, 4 pp
Language:        English
Available from:    American Academy of Pediatrics, Department of Maternal, Child, and Adolescent Health, Committee on Pediatric AIDS, 141 NW Point Blvd, Elk Grove Village, IL 60007; 847-434-4000; www.aap.org

Screening for Tuberculosis and Tuberculosis Infection in High-Risk Populations. Morbidity and Mortality Weekly Report. 4(RR-11), September 9, 1995 CDC Icon
This report updates previous recommendations regarding screening for TB infection and disease among high-risk populations (Centers for Disease Control and Prevention, 1995).
Audience: health professionals, nurses, physicians
Format: report, 15 pp
Language:        English
Internet link: www.cdc.gov/nchstp/tb/pubs/mmwrhtml/maj_guide.htm
Available from:    CDC National Center for HIV, STD, and TB Prevention (NCHSTP). Materials can be ordered in a number of ways: 1) By accessing the online order form at www.cdc.gov/nchstp/tb; 2) by calling the CDC voice and fax information system (recording) toll-free at 888-232-3228, then pressing options 2, 5, 1, 2, 2; 3) by faxing a request for material to the NCHSTP Office of Communications at 404-639-8910; or 4) by mailing a request to the CDC NCHSTP Office of Communications at 1600 Clifton Rd, NE, MS E-07, Atlanta, GA 30333. Request item #00-6617.    
and   CDC National Prevention Information Network, PO Box 6003, Rockville, MD 20849 -6003; 800-458-5231; www.cdcnpin.org. Request inventory item #D372.    
and   Massachusetts Medical Society, 860 Winter St, Waltham Woods Corporate Center, Waltham, MA 02451-1411; 800-843-6356; www.massmed.org. Paper copies of single issues cost $5.25.    
and   U.S. Government Printing Office (GPO), Washington, D.C. 20402; 866-512-1800; www.gpo.gov. GPO provides a CD-ROM containing MMWRs from 1991 to 1997 for $19. Request item #017-022 -01418-1.

Tuberculin Skin Testing of Inpatients in Connecticut Hospitals: Recommendations of the Connecticut Tuberculosis Elimination Advisory Committee
This report discusses the epidemiology of TB in Connecticut and the state control of TB through screening and medical treatment. It defines TB, TB infection, HIV, and TB/HIV co-infection. It provides specific information about state reporting requirements for TB cases and discusses management techniques for the care of TB-infected persons (American Lung Association of Connecticut, 1995).
Audience:         physicians
Format: report, 8 pp
Language:        English
Available from:    American Lung Association of Connecticut, 45 Ash St, East Hartford, CT 06108-2372; 800 -LUNG-USA, 860-289-5407; www.alact.org

Tuberculosis School Nurse Handbook
This handbook discusses screening school children for TB disease and infection, and administering medications (New Jersey Medical School, National Tuberculosis Center, 2001).
Audience:   nurses
Format: book, 30 pp
Language:        English
Internet link: www.umdnj.edu/ntbcweb/pr_frame.html
Available from:    University of Medicine and Dentistry of New Jersey, New Jersey Medical School, National Tuberculosis Center, 225 Warren St, First Fl, West Wing, PO Box 1709, Newark, NJ 07101-1709; 973-972 -0979; www.umdnj.edu/ntbcweb

Chest Radiographs

Diagnosis: The Chest Radiograph Following a Positive Tuberculin Skin Test
This fact sheet provides information on the use of chest radiographs in the TB diagnostic process. It provides guidelines on what to do following a negative chest radiograph and how employers who require regular chest radiographs can align their policies with those of New York City, New York state, and the federal government (New York City Department of Health, 2001).
Audience: health professionals, nurses, physicians
Format: fact sheet, 1 p
Language:        English
Internet link: www.nyc.gov/html/doh/html/tb/tb1d.html
Available from:    New York City Department of Health and Mental Hygiene, Tuberculosis Control Program, 125 Worth St, New York, NY 10013; 212-442-9968; www.nyc.gov/html/doh/html/tb/tb.html

Radiographic Manifestations of Tuberculosis: A Primer for Clinicians
This study guide discusses how to read a chest radiograph and radiographic manifestations of TB, and presents case studies (Francis J. Curry National Tuberculosis Center, 2002).
Audience:         physicians
Format: study guide
Language:        English
Available from:    Francis J. Curry National Tuberculosis Center, 3180 18th St, Ste 101, San Francisco, CA 94110-2028; 415-502-4600; www.nationaltbcenter.edu

Sputum Smear Examination

Acid-Fast Direct Smear Microscopy CDC Icon
This information packet is designed to assist laboratories in performing direct AFB microscopy. It complements laboratory manuals by demonstrating appropriate technique, emphasizing standard methods, and promoting consistent reading and reporting of smear results (Centers for Disease Control and Prevention, 2001).
Audience: health professionals, Hispanics, lab personnel
Format: information packet (book, videotape, audiocassette, slide set)
Language:      English, French, Russian, Spanish
Internet link: English: www.phppo.cdc.gov/dls/afb/default.asp          French: www.phppo.cdc.gov/dls/afb/default.asp#t2          Spanish: www.cdc.gov/spanish/enfermedades/tb/baar.htm
Available from:    CDC Division of Laboratory Systems, 1600 Clifton Rd, Atlanta, GA 30333; 800-311-3435, 404-639-3534; www.phppo.cdc.gov/dls/default.asp

Conducting Sputum Induction Safely
This guideline provides TB control staff at high-risk institutions (e.g., health care facilities, correctional facilities, shelters) with practice-based guidance on conducting sputum induction safely. It addresses appropriate engineering controls and proper administrative controls (Francis J. Curry National Tuberculosis Center, 1999).
Audience: correctional personnel, health educators/communicators, health professionals, nurses, occupational health and infection control workers, physicians
Format: guideline, 51 pp
Language:        English
Available from:    Francis J. Curry National Tuberculosis Center, 3180 18th St, Ste 101, San Francisco, CA 94110-2028; 415-502-4600; www.nationaltbcenter.edu

Management: Monitoring Sputum During TB Treatment
This fact sheet discusses the use of sputum testing to monitor patients with active pulmonary TB. It provides recommendations regarding when to obtain a sputum specimen and where individuals can go to receive a sputum induction in New York City (New York City Department of Health, 2001).
Audience: health professionals, physicians
Format: fact sheet, 1 p
Language:        English
Internet link: www.nyc.gov/html/doh/html/tb/tb2c.html
Available from:    New York City Department of Health and Mental Hygiene, Tuberculosis Control Program, 125 Worth St, New York, NY 10013; 212-442-9968; www.nyc.gov/html/doh/html/tb/tb.html

Culture Examination

Diagnosis: Culture Negative Tuberculosis
This fact sheet discusses the diagnosis and treatment of TB in patients who do not render a positive culture from conventional TB practices (New York City Department of Health, 2001).
Audience: health professionals, nurses, physicians
Format: fact sheet, 2 pp
Language:        English
Internet link: www.nyc.gov/html/doh/html/tb/tb1i.html
Available from:    New York City Department of Health and Mental Hygiene, Tuberculosis Control Program, 125 Worth St, New York, NY 10013; 212-442-9968; www.nyc.gov/html/doh/html/tb/tb.html

Diagnosis: False-Positive Cultures for Mycobacterium Tuberculosis
This fact sheet discusses proper diagnosis of TB when false-positive cultures are found in laboratory tests (New York City Department of Health, 2001).
Audience: health professionals, nurses, physicians
Format: fact sheet, 2 pp
Language:        English
Internet link: www.nyc.gov/html/doh/html/tb/tb1b.html
Available from:    New York City Department of Health and Mental Hygiene, Tuberculosis Control Program, 125 Worth St, New York, NY 10013; 212-442-9968; www.nyc.gov/html/doh/html/tb/tb.html

Misdiagnoses of Tuberculosis Resulting from Laboratory Cross-Contamination of Mycobacterium Tuberculosis Cultures—New Jersey, 1998. Morbidity and Mortality Weekly Report. 49(19):413-416, May 19, 2000 CDC Icon
This report describes findings from two cases in which TB was misdiagnosed due to laboratory cross-contamination and summarizes the results of the ensuing investigation, which demonstrated the value of DNA fingerprinting to identify occurrences of cross-contamination among patient specimens (Centers for Disease Control and Prevention, 2000).
Audience: health professionals, nurses, physicians
Format: report, 4 pp
Language:        English
Internet link: www.cdc.gov/nchstp/tb/pubs/mmwrhtml/mmwr_laboratory.htm
Available from:    Massachusetts Medical Society, 860 Winter St, Waltham Woods Corporate Center, Waltham, MA 02451-1411; 800 -843-6356; www.massmed.org. Paper copies of single issues cost $5.25.

Packaging and Shipping Specimens for Culture of Mycobacterium Tuberculosis
This guideline instructs the reader about how to handle a sputum sample for transportation (Mississippi State Department of Health, 1996).
Audience: health professionals, nurses, physicians
Format: guideline, 1 p
Language:        English
Available from:    Mississippi State Department of Health, Tuberculosis Control Branch, PO Box 1700, Jackson, MS 39215-1700; 601-576-7400; www.msdh.state.ms.us

Recognition and Prevention of False-Positive Test Results in Mycobacteriology
This information packet discusses ways to prevent false-positive readings on TB-related diagnostic tests. It explains what it means to obtain a false-negative TB test, why tests sometimes get false readings, what testing conditions may lead to false readings, ways to prevent false-positive tests, and how recording tools can help pinpoint false-positive test results (Association of Public Health Laboratories, 1997).
Audience: health professionals, lab personnel, nurses, physicians
Format: information packet (1 book, 1 videotape)
Language:        English
Available from:    Association of Public Health Laboratories, 2025 M St, NW, Ste 550, Washington, DC 20036; 202-822-5227; www.aphl.org

Other Laboratory Procedures

Diagnosis: Diagnostic Tests for Tuberculosis
This fact sheet examines recent improvements in TB testing technologies that allow for faster laboratory diagnosis of TB. It explains how nucleic acid amplification (NAA) tests have helped laboratories diagnose patients more quickly and outlines the limitations of NAA tests (New York City Department of Health, 2001).
Audience: health professionals, lab personnel, nurses, physicians
Format: fact sheet, 2 pp
Language:        English
Available from:    New York City Department of Health and Mental Hygiene, Tuberculosis Control Program, 125 Worth St, New York, NY 10013; 212-442-9968; www.nyc.gov/html/doh/html/tb/tb.html

Diagnosis: Rapid Diagnostic Tests for Tuberculosis
This fact sheet discusses advances in laboratory diagnostic methods, their use and interpretation, and their limitations (New York City Department of Health, 2000).
Audience: health professionals, physicians
Format: fact sheet, 2 pp
Language:        English
Internet link: www.nyc.gov/html/doh/html/tb/tb1g.html
Available from:    New York City Department of Health and Mental Hygiene, Tuberculosis Control Program, 125 Worth St, New York, NY 10013; 212-442-9968; www.nyc.gov/html/doh/html/tb/tb.html

Laboratory Practices for Diagnosis of Tuberculosis—United States, 1994. Morbidity and Mortality Weekly Report. 44(31):587-589, August 11, 1995 CDC Icon
This report summarizes information reported to proficiency testing programs by laboratories in the United States about their practices for Mycobacterium tuberculosis (Centers for Disease Control and Prevention, 1995).
Audience: health professionals, lab personnel, nurses, physicians
Format: report, 3 pp
Language:        English
Internet link: www.cdc.gov/nchstp/tb/pubs/mmwrhtml/mmwr_laboratory.htm
Available from:    Massachusetts Medical Society, 860 Winter St, Waltham Woods Corporate Center, Waltham, MA 02451-1411; 800 -843-6356; www.massmed.org. Paper copies of single issues cost $5.25.    
and   U.S. Government Printing Office (GPO), Washington, D.C. 20402; 866-512-1800; www.gpo.gov. GPO provides a CD-ROM containing MMWRs from 1991 to 1997 for $19. Request item #017-022 -01418-1.

Nucleic Acid Amplification Tests for Tuberculosis. Morbidity and Mortality Weekly Report. 45(43):950-952, November 1, 1996 CDC Icon
This report summarizes potential uses of nucleic acid amplification (NAA) tests for TB diagnosis and provides interim guidelines for the use of such tests (Centers for Disease Control and Prevention, 1996).
Audience: health professionals, lab personnel, nurses, physicians
Format: report, 3 pp
Language:        English
Internet link: www.cdc.gov/nchstp/tb/pubs/mmwrhtml/mmwr_laboratory.htm
Available from:    Massachusetts Medical Society, 860 Winter St, Waltham Woods Corporate Center, Waltham, MA 02451-1411; 800 -843-6356; www.massmed.org. Paper copies of single issues cost $5.25.    
and   U.S. Government Printing Office (GPO), Washington, D.C. 20402; 866-512-1800; www.gpo.gov. GPO provides a CD-ROM containing MMWRs from 1991 to 1997 for $19. Request item #017-022 -01418-1.

QuantiFERON-TB®
This fact sheet describes the advantages of testing for TB using QuantiFERON-TB® (Cellestis, Inc., 2002).
Audience: nurses, physicians
Format: fact sheet, 2 pp
Language:        English


Available from:    Cellestis, Inc., 28005 North Smyth Dr, Valencia, CA 91355; 661-295-4627; www.cellestis.com

Update: Nucleic Acid Amplification Tests for Tuberculosis. Morbidity and Mortality Weekly Report. 49(26):593-594, July 7, 2000 CDC Icon
This notice explains that on September 30, 1999, the Food and Drug Administration approved a reformulated amplified Mycobacterium Tuberculosis Direct (MTD) test for detection of Mycobacterium tuberculosis in acid-fast Bacille (AFB) smear-positive and smear-negative respiratory specimens from patients suspected of having TB (Centers for Disease Control and Prevention, 2000).
Audience: health professionals, lab personnel, nurses, physicians
Format: report, 2 pp
Language:        English
Internet link: www.cdc.gov/nchstp/tb/pubs/mmwrhtml/mmwr_laboratory.htm
Available from:    Massachusetts Medical Society, 860 Winter St, Waltham Woods Corporate Center, Waltham, MA 02451-1411; 800 -843-6356; www.massmed.org. Paper copies of single issues cost $5.25.


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