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Home Field Advantage: Intravaginal Immunization May Help Protect Against Infection

Abstract
Researchers led by John Schiller at the National Cancer Institute have published a study exploring the immune response to intravaginal immunization in mice infected with a strain of the HPV virus carrying a certain antigen. The researchers found that intravaginal immunization significantly increased the number of immune cells present in the vaginal mucosa as compared to a general immune system booster. The results show that area-specific vaccination enhances the local immune system response and may be helpful in developing STD vaccines. The study titled,'Intravaginal Immunization with HPV Vectors Induces Tissue-Resident CD8+ T cell Responses' is published online in the Journal of Clinical Investigation (2012; doi:10.1172/JCI63287).
Source
http://medicalxpress.com
Date of Publication
11/12/2012
Article Type
General media
Article Category
News Briefs

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cdcnpin.org News Record #60729

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