Cohort Studies of HIV/AIDS and Substance Use (U01)
Grant Amount: Unspecified.
This Funding Opportunity Announcement (FOA), issued by the National Institute on Drug Abuse (NIDA), invites grant applications that propose longitudinal cohort studies to address emerging and/or high priority research on HIV/AIDS and substance abuse. The initiative is intended to develop new cohorts or build on existing cohorts, which include substance using individuals who are HIV positive or at risk for infection. The applications in response to this FOA may include specific research projects that focus on the intersection of HIV/AIDS and substance use, and should serve as a platform for a wide range of research efforts by the investigator, collaborators, and other researchers utilizing data and/or specimens collected from these studies as part of independent, investigator-initiated research grants. Research aims included in submitted applications may be broad or narrow, given the diverse topics of interest to this FOA, such as identifying the determinants of susceptibility or resistance to infection; HIV prevention; barriers to optimal HIV care; the effects of multiple co-morbidities and co-infections, such as HBV and HCV; disease progression and response to both substance abuse and HIV treatment; the impact of aging; factors affecting adherence to antiretroviral treatment and other pharmacotherapeutic and behavioral interventions; and understanding determinants and consequences of comprehensive care for chronic comorbid diseases, substance abuse, and mental health issues. Populations of particular interest may include injection and non-injection substance users, sexual minorities (including men who have sex with men (MSM)), racial and ethnic minorities women, youth/adolescents, and high-risk heterosexual couples .
The National Institute on Drug Abuse encourages data harmonization to increase comparability, collaboration, and scientific yield of research funded under this FOA. The capacity of cohort studies to address both broad and specific research questions that take into account the heterogeneity among HIV-infected and at-risk individuals, the diversity of disease severity, patterns and history of substance use, comorbidities, and demographic variables, would be greatly enhanced by harmonization using a common set of core measures. Common elements for interval data collection provide opportunities for multiple cohorts addressing a variety of issues to collaborate on priority questions of mutual interest, which a single cohort may not be able to address. Awardees funded under this FOA will be expected to participate in collaborative activities, including annual meetings to determine how to best to harmonize data. Applications in response to this FOA should include funds for investigators to attend an annual meeting in Washington, D.C. as part of the budget request.
National Institute on Drug Abuse
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Award Amount Notes
The number of awards is contingent upon NIH appropriations, and the submission of a sufficient number of meritorious applications.
Award Budget Application budgets are not limited, but need to reflect actual needs of the proposed project.
Letter of Intent Date
Application Due Date
Project Start Date
Grants.gov Customer Support , Phone: (800) 518-4726
Jag H Khalsa Chief, Medical Consequences Branch DPMCNIDA/NIH 6001 Executive Boulevard Room 4137, MSC 9551 Bethesda, MD 208929551 Phone: (301) 443-2159 Fax: (301) 443-2599
Up to 5 years.
Antiretroviral Drugs Behavioral Research HIV/AIDS Prevention Pharmaceutical Research Research Programs Substance Abuse Treatment and Counseling
At Risk Persons At Risk Youth HIV Positive Persons Researchers Substance Abusers
Applicants must download the SF424 (R&R) application package associated with this funding opportunity using the “Apply for Grant Electronically” button in this FOA or following the directions provided at Grants.gov.
It is critical that applicants follow the instructions in the SF424 (R&R) Application Guide (http://grants.nih.gov/grants/funding/424/SF424_RR_Guide_General_Adobe_VerB.pdf), except where instructed in this funding opportunity announcement to do otherwise. Conformance to the requirements in the Application Guide is required and strictly enforced. Applications that are out of compliance with these instructions may be delayed or not accepted for review.
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