HIV Vaccine Research and Design (HIVRAD) Program (P01)
Grant Amount: Estimated total $5M for fiscal year 2015.
The HIVRAD program is designed to fund projects that further address hypotheses crucial to the design of an efficacious HIV/AIDS prophylactic vaccine. Applications for five years of support should include plans that have advanced past the exploratory stage and include preliminary data. Less fully developed applications can request less than 5 years of support to establish feasibility. Applications aimed at developing or optimizing a specific vaccine platform should lay out a research pathway with clear decision points. Extensive modeling of vaccine concepts in non-human primates may be included.
Clinical studies involving human subjects or vaccine research focused solely on therapeutic applications are not considered appropriate and will not be funded under this FOA. For information on programs that support therapeutic vaccine development, please contact program staff.
Applications may address, but need not be limited to:
Approaches to elicit durable and broadly neutralizing antibodies against HIV and/or SIV; Identifying correlates of vaccine-induced immune protection to HIV/AIDS; HIV structural studies as they relate to designing HIV immunogens; Improved animal model systems (and challenge viruses) to address vaccine efficacy; Approaches to increase the immunogenicity of HIV antigens (e.g., novel adjuvants); How vaccine design can better address the heterogeneity of HIV; Developing or improving viral or bacterial vaccine vectors; Determining how immune cells can be mobilized to the portal of infection; Investigations into the role of glycan structures on immunogenicity, antigenicity and infectivity; Investigations into innate immunity to alter the outcome of infection.
National Institute of Allergy and Infectious Diseases Division of AIDS
City Agencies Colleges/Universities Commercial Organizations Community Based Organizations County Agencies Educational Organizations/Institutions Federal Government Agencies International Agencies IRS 501 (c)(3) Organizations Nonprofit Organizations Religious Organizations Schools State Agencies Tribal Organizations
Number of Awards Given
1 - 3 awards
Award Amount Notes
NIH intends to fund an estimate of 1-3 awards, corresponding to a total of $5M, for fiscal year 2015. Future year amounts will depend on annual appropriations.
Applicants must download the SF424 (R&R) application package associated with this funding opportunity using the “Apply for Grant Electronically” button in this FOA or following the directions provided at Grants.gov.
It is critical that applicants follow the instructions in the SF424 (R&R) Application Guide (http://grants.nih.gov/grants/funding/424/SF424_RR_Guide_General_Adobe_VerB.pdf), except where instructed in this funding opportunity announcement to do otherwise. Conformance to the requirements in the Application Guide is required and strictly enforced. Applications that are out of compliance with these instructions may be delayed or not accepted for review.
Disclaimer: NPIN provides this information as a public service only. The views and information provided about the materials, funding opportunities, and organizations do not necessarily state or reflect those of the U.S. Department of Health and Human Services, CDC, or NPIN.