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Comorbid HIV, Chronic Pain, and Substance Use among Older Adults (R21)

Grant Amount: NIH intends to commit $1 million in FY2014 to fund an estimated 5-7 awards.

To improve understanding of the intersection of HIV/AIDS and drug abuse, this Funding Opportunity Announcement (FOA) is part of a multipronged 2014 expansion of HIV and AIDS related research within the context of drug and alcohol abuse among understudied populations and in understudied settings that show promise for the development of effective prevention and treatment efforts. In addition to this funding opportunity, others included in the 2014 expansion address HIV/AIDS and substance use among the homeless and unstably housed (RFA-DA-14-009); substance use, HIV, and Black/African American women and young Men who have Sex with Men (MSM) (RFA-DA-14-010); the integration of substance abuse and HIV prevention and treatment within HIV/AIDS service delivery settings (RFA-DA-14-011) and Seek, Test, Treat, and Retain Data Harmonization Coordinating Center (RFA-DA-14-007).

For this funding announcement, the National Institute on Drug Abuse (NIDA) invites innovative, exploratory research applications proposing to study the intersection of HIV, chronic pain, and substance use among older adults. Applications could include research to examine risk and protective factors contributing to comorbid HIV, chronic pain, and substance use among older adults; to characterize the adverse medical, mental health and social consequences associated with comorbid HIV, substance abuse, and chronic pain among older adults; or to develop effective prevention and service delivery approaches and behavioral and pharmacological treatments to address these comorbid conditions in older adults. Research is also encouraged on the role of HIV/AIDS-associated conditions, HIV treatment, and/or other biobehavioral/social factors in the context of aging, chronic pain, and substance use. A range of research approaches are of interest, including epidemiologic, prevention science, health services, and intervention studies.
Funding Organization
National Institute on Drug Abuse
Fund Category
Support Types
Eligible Organizations
City Agencies
Commercial Organizations
Community Based Organizations
County Agencies
Educational Organizations/Institutions
Federal Government Agencies
IRS 501 (c)(3) Organizations
Nonprofit Organizations
Religious Organizations
State Agencies
Tribal Organizations
Number of Awards Given
5 - 7 awards
Award Amount Notes
NIH intends to commit $1 million in FY2014 to fund an estimated 5-7 awards.
Letter of Intent Date
Application Due Date
Project Start Date
Application Contact
Phone: (301) 435-0714
Technical Contact
Jeffrey D Schulden
Epidemiology Research BranchDESPR

Phone: (301) 402-1526
Fund Duration
Up to 2 years.
Adverse Reactions
Alcohol Abuse
Behavioral Research
Drug Abuse
Health Care Programs/Services
HIV/AIDS Prevention
Medical Treatments and Therapies
Mental Health Services
Older Adults
Research Programs
Application Process
Applicants must download the SF424 (R&R) application package associated with this funding opportunity using the “Apply for Grant Electronically” button in this FOA or following the directions provided at

It is critical that applicants follow the instructions in the SF424 (R&R) Application Guide (, except where instructed in this funding opportunity announcement to do otherwise. Conformance to the requirements in the Application Guide is required and strictly enforced. Applications that are out of compliance with these instructions may be delayed or not accepted for review.
Companion Funding Opportunity: RFA-DA-14-009, R01 Research Project Grant; RFA-DA-14-010, R01 Research Project Grant; RFA-DA-14-011, R01 Research Project; RFA-DA-14-007, U01 Research Project – Cooperative Agreements.
Web Site
Fund Number

Disclaimer: NPIN provides this information as a public service only. The views and information provided about the materials, funding opportunities, and organizations do not necessarily state or reflect those of the U.S. Department of Health and Human Services, CDC, or NPIN. Fund Record #4726

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