Ethical Issues in Research on HIV/AIDS and its Co-morbidities (R21)
Grant Amount: Unspecified.
Since the beginning of the HIV epidemic, research on HIV/AIDS has raised ethical challenges. The rapidly emerging epidemic and corresponding research and clinical care responses have made these ethical tensions highly visible. Controversies have arisen over clinical trial design, access to drugs, regulatory approval pathways, stigmatized populations, and global health disparities. The populations at risk for acquiring or living with HIV are often economically, socially or politically vulnerable, and HIV transmission is frequently linked to socially sensitive behaviors. These characteristics have heightened the ethical tensions in HIV/AIDS research, across the spectrum from observational studies, early phase/translational trials, product development, behavioral research, and public health intervention.
Applications for support under this FOA may include conceptual work in bioethics, or empirical work gathering and analyzing data relevant to ethical issues in research, or a combination of the two. For empirical projects, data collection may include quantitative or qualitative methods, or both.
For all applications, the research team is strongly encouraged to include at least one person with demonstrated expertise and scholarship in bioethics, as demonstrated by academic work and publications in the field.
For projects involving empirical data collection, applicants should describe how the data collection will inform current or future ethical deliberations or ethical oversight processes; the research team should include at least one social scientist or other researcher with relevant expertise in theory and methodology for conducting the proposed empirical research.
For projects which are purely conceptual or analytical bioethics work and do not involve empirical investigation, applicants should describe: the current state of scholarship on the topic; why the proposed project is significant and innovative, for example, whether new reasoning is applied to a familiar problem, or whether a new problem is addressed; and what type of theoretical framework or approach will be used to address the problem.
For projects which combine conceptual work in bioethics with empirical data collection, applicants should describe how the data collection informs ethical analysis or decision making, in addition to addressing the requirements for conceptual work as stated above.
The following selected bioethics topics are of particular interest; however, other ethical issues are relevant and this list is not intended to be exhaustive: Ethical Issues in Research Utilizing Human Specimens; Ethics of Research Involving Pregnant Women; Ethics of Research Involving Adolescents and Young Adults; Ethical Issues in Research on an HIV Cure; Standards of Care and the Interaction of Statistics and Ethics in Clinical Trial Design; Effectiveness of Research Ethics Committee Review; Ethical Issues in HIV Research Using New Forms of Technology; Research in Settings of Stigma, Discrimination and Oppression; Ethical Issues in Research Related to HIV and Tuberculosis (TB); Research on Community Engagement: Principles and Practices; Research on Community Engagement: Principles and Practices.
National Institute of Allergy and Infectious Diseases National Institute on Drug Abuse US Department of Health and Human Services Division of AIDS Eunice Kennedy Shriver National Institute of Child Health and Human Development National Cancer Institute Public Health Services National Institutes of Health Office of Communications National Institute of Mental Health
City Agencies Colleges/Universities Commercial Organizations Community Based Organizations County Agencies Educational Organizations/Institutions Federal Government Agencies International Agencies IRS 501 (c)(3) Organizations Nonprofit Organizations Religious Organizations Schools State Agencies Tribal Organizations
Award Amount Notes
The number of awards is contingent upon NIH appropriations, and the submission of a sufficient number of meritorious applications.
Application Due Date
Project Start Date
Grants.gov Customer Support , Phone: (800) 518-4726
Adolescents Clinical Trials HIV Medical Treatments and Therapies Patient Care Pregnancy Research Programs TB
Applicants must download the SF424 (R&R) application package associated with this funding opportunity using the “Apply for Grant Electronically” button in this FOA or following the directions provided at Grants.gov.
It is critical that applicants follow the instructions in the SF424 (R&R) Application Guide (http://grants.nih.gov/grants/funding/424/SF424_RR_Guide_General_Adobe_VerB.pdf), except where instructed in this funding opportunity announcement to do otherwise. Conformance to the requirements in the Application Guide is required and strictly enforced. Applications that are out of compliance with these instructions may be delayed or not accepted for review.
Companion Funding Opportunity: PAR-12-244, R01 Research Project Grant.
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