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Funding

Demonstration Project of Elective Adult Male Circumcision Conducted in Sexually Transmitted Disease (STD) Clinics in the United States (U18)

Description
Grant Amounts: The participating Centers, Institutes and Offices (CIO)(s), NCHHSTP, intends to commit approximately $155,000, including direct and indirect cost dollars in FY2009 to fund 2 applications. An applicant may request a project period of up to 4 years. It is anticipated that costs will be highest in years 2 and 3, during which time enrollment and participant follow-up would occur.

The Centers for Disease Control and Prevention (CDC) announces the availability of fiscal year (FY) 2009 funds for a cooperative agreement program called "Demonstration Project of Elective Adult Male Circumcision Conducted in Sexually Transmitted Disease (STD) Clinics in the United States."

Applicants to this demonstration project must include all of the following components related to adult male circumcision in their research plan: (1) acceptability and uptake; (2) healing after surgery; (3) adverse events and side effects associated with circumcision; (4) whether circumcision is associated with changes in sexual behavior; (5) the rates of incident sexually transmitted diseases acquired after circumcision; and (6) relevant data on cost and feasibility of larger scale adult circumcision services in the United States.

Applicants need to enroll HIV-negative uncircumcised heterosexual men who are outpatients at STD clinics; these men would be presumed to be at high risk for acquisition of HIV infection through penile-vaginal (heterosexual) transmission. Populations of particular interest are those which may have lower overall circumcision rates, including Hispanics and foreign-born men, e.g., from parts of sub-Saharan Africa with low circumcision rates, and the Caribbean. Enrollees would be counseled about the benefits and risks of male circumcision, and offered the procedure free of charge. The men would need to be followed for a minimum of 4 months and monitored periodically for laboratory-confirmed sexually transmitted diseases, changes in sexual behavior, and adverse events associated with circumcision. Two sites with proven capacity would be selected, with the goal of screening and enrolling enough men to result in 50 surgical circumcisions per site. At least one site would serve a largely Hispanic clientele. Data from the two sites would be pooled in a combined analysis; data would be submitted to and analyzed at CDC.







Funding Organization
National Center for US Department of Health and Human Services
Public Health Service
Centers for Disease Control and Prevention
National Center for HIV/AIDS Viral Hepatitis STD and TB Prevention
Fund Category
HIV/AIDS
Support Types
Cooperative Agreements
Locations
National
Eligible Organizations
City Agencies
Colleges/Universities
Commercial Organizations
Community Based Organizations
County Agencies
Hospitals
Minority Owned Organizations
Nonprofit Organizations
Religious Organizations
Research Institutions
State Agencies
Tribal Organizations
Woman Owned Organizations
Number of Awards Given
2 awards
Award Amount Notes
The participating Centers, Institutes and Offices (CIO)(s), NCHHSTP, intends to commit approximately $155,000, including direct and indirect cost dollars in FY2009 to fund 2 applications. The average award amount will be $75,000 to $80,000 per awardee including both direct and indirect costs for the first 12-month budget period. An applicant may request up to $80,000 for the first 12 months. An applicant may request a project period of up to 4 years. It is anticipated that costs will be highest in years 2 and 3, during which time enrollment and participant follow-up would occur. For this reason, NCHHSTP intends to commit $300,000 each year in FY2010 and in FY2011, with projected yearly award amounts of $150,000 per awardee. In the final year of funding, FY2012, NCHHSTP intends to commit $200,000, with projected award amounts of $100,000. The approximate total project period funded amount is $955,000.

CDC will not accept and review applications with budgets greater than the ceiling amount.

Because the nature and scope of the proposed research will vary from application to application, it is anticipated that the size and duration of each award will also vary. Although the financial plans of the CIO (s) provide support for this program, awards pursuant to this funding opportunity are contingent upon the availability of funds and the receipt of a sufficient number of meritorious applications.
Application Due Date
3/3/2009
Project Start Date
8/15/2009
Application Contact
Louvern Asante
Procurement & Grants Office
CDC/DHHS
2920 Brandywine Rd, MS E-15
Atlanta, GA 30341
Phone: (404) 639-8291
Technical Contact
Shoukat Qari
Extramural ProgramsStrategic Sci & Program Unit
Coordinating Ctr for Inf Disease
CDC/DHHS
1600 Clifton Rd, MS E-60
Atlanta, GA 30333
Phone: (404) 498-2274
Fax: (404) 498-2626
Fund Duration
Up to four years.
Subjects
Adults
Adverse Reactions
Heterosexuals
HIV/AIDS Prevention
Risk Reduction
Sexual Behavior or Behaviors
Sexually Transmitted Diseases (STDs)
Audiences
Heterosexuals
Men
Application Process
Applications submitted in response to this Funding Opportunity Announcement (FOA) for Federal assistance must be submitted electronically through Grants.gov (http://www.grants.gov) using the SF424 Research and Related (R&R) forms and the SF424 (R&R) Application Guide.

Applicants must download the SF424 (R&R) application forms and SF424 (R&R) Application Guide for this FOA through Grants.gov/Apply.

Note: Only the forms package directly attached to a specific FOA can be used. You will not be able to use any other SF424 (R&R) forms (e.g., sample forms, forms from another FOA); although some of the "Attachment" files may be useable for more than one FOA.

For further assistance, contact PGO TIMS: Telephone 770-488-2700, Email: PGOTIM@cdc.gov

HHS/CDC Telecommunications for the hearing impaired: TTY 770-488-2783.

Web Site
http://www.cdc.gov/od/pgo/funding/PS09-005.htm
Fund Number
RFA-PS-09-005

Disclaimer: NPIN provides this information as a public service only. The views and information provided about the materials, funding opportunities, and organizations do not necessarily state or reflect those of the U.S. Department of Health and Human Services, CDC, or NPIN.

cdcnpin.org Fund Record #3731

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