Mucosal Environment and HIV Prevention (MEHP) (R01)
Grant Amount: NIAID/DAIDS intends to commit $3,500,000 to fund 4 to 8 awards; NICHD/CPR/DBS intends to commit $2,400,000 to fund 4 to 6 awards.
The National Institute of Allergy and Infectious Diseases (NIAID) and the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), National Institutes of Health, encourages grant applications from institutions/organizations that address the goals and objectives of this funding opportunity announcement (FOA). The Mucosal Environment and HIV Prevention (MEHP) FOA is intended to support innovative proof-of-concept/feasibility non-vaccine biomedical prevention (nBP) research needed to support and advance the development of safer and more effective microbicides, Pre-Exposure Prophylaxis (PrEP), and Multipurpose Prevention Technologies (MPT). It will achieve this by supporting a better understanding of prevention candidates and strategy interaction with the micro- and macro-environments of the genital (male and female) and gastrointestinal (GI) mucosa. The MEHP FOA addresses the following 3 underserved emerging areas of Program interest: role of the microbiome in transmission/acquisition of HIV and candidate safety and efficacy, tissue responses to prevention agents, and the effect of genital secretions and hormones on susceptibility to HIV infection:
The MEHP is intended to support innovative basic research efforts, which may or may not involve an active pharmaceutical ingredients (APIs), formulation/excipient and/or device currently under development. The MEHP FOA is not intended to support the preclinical or clinical development of new nBP candidates or their delivery systems. The MEHP concept has been previously released as PA-12-106, and applicants are urged to read this FOA carefully, since there are differences from the PA that could alter responsiveness.
National Institute of Allergy and Infectious Diseases National Institutes of Health Division of Intramural Research Eunice Kennedy Shriver National Institute of Child Health and Human Development
City Agencies Colleges/Universities Commercial Organizations Community Based Organizations County Agencies Educational Organizations/Institutions Federal Government Agencies International Agencies IRS 501 (c)(3) Organizations Nonprofit Organizations Religious Organizations Schools State Agencies Tribal Organizations
Award Amount Notes
The following NIH components intend to commit the following amounts in FY 2014: NIAID/DAIDS intends to commit $3,500,000 to fund 4 to 8 awards. NICHD/CPR/DBS intends to commit $2,400,000 to fund 4 to 6 awards.
Applicants must download the SF424 (R&R) application package associated with this funding opportunity using the “Apply for Grant Electronically” button in this FOA or following the directions provided at Grants.gov.
It is critical that applicants follow the instructions in the SF424 (R&R) Application Guide (http://grants.nih.gov/grants/funding/424/SF424_RR_Guide_General_Adobe_VerB.pdf), except where instructed in this funding opportunity announcement to do otherwise. Conformance to the requirements in the Application Guide is required and strictly enforced. Applications that are out of compliance with these instructions may be delayed or not accepted for review.
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